The IMPACT Study offers free PrEP medicine to people at risk of catching HIV. Visit the trial website for more information. Call the number below if you have any questions.

We are recruiting new participants until July 12th 2020. Everyone on the study is eligible for free meds until NHS PrEP launches.

You can make an appointment at Dean Street Express in Soho by calling 020 3315 5656. Existing Dean Street patients can book an appointment to join the study by clicking HERE.

Study closure visits begin from 12th July. At that visit participants will be offered a further 3 month supply of PrEP to last until NHS PrEP launches.



PreP Shop

PrEP Shop remains open during COVID-19. Please call us to arrange a time slot to register or for your kidney tests (020 3315 5656).

We’ve created PrEP Shop to make it easier for you to buy generic HIV PrEP from someone you trust. By using the buying power of the NHS we aim to keep prices as affordable as we can. Please find our pricing structure below, we can offer a discount if you buy multiple packs.



Gay men aged under 25 years old can request free PrEP through the clinic’s ‘Generation ZERO’ fund. We can prescribe up to 3 months of free PrEP at a time. If you can afford it we ask to contribute by making a donation back to the fund. If you can’t afford anything, that’s fine.

If you’re taking PrEP, it’s really important to get the right advice, run some tests, check you don’t have Hepatitis B , make sure that any other drugs or supplements you take don’t interact with PrEP and that you don’t have any other health problems that might be an issue. PrEP Shop keeps things safe by linking all these things with the doctors and pharmacists who write and check your prescriptions.

HIV PrEP (Pre-exposure prophylaxis) involves taking pills containing the drugs tenofovir & emtricitabine to protect you from catching HIV. It works really well if you take it correctly. For more information about PrEP and how to take it, visit our YouTube playlist. We recommend that you read this PrEP leaflet on the ‘i-Base’ website.

How do I buy from PrEP Shop?

There’s some paperwork we need to complete with you before we are allowed to prescribe you PrEP. We’ll need to register you for ‘Additional Private Care’ and then run some tests to check it’s safe to prescribe you it.

Tell us that you want to buy from ‘PrEP Shop’ during your visit to ‘56 Dean Street’ or ‘Dean Street Express’. We’ll explain how ‘Additional Private Care’ works and ask you to sign the paperwork.

  • We’ll ask about your medical history and if you’re taking other medicines.
  • We’ll check your kidney blood and urine tests.
  • We’ll check your Hepatitis B result.
  • After your appointment, we’ll ask you to email ‘PrEP Shop’ with your name, clinic number & your request (Maximum 7 month supply between check ups).
  • We’ll text you a few days later to let you know that our doctor has checked the results and prescribed your medicines.
  • You come in, pay and collect your PrEP tablets from 56 Dean Street.
  • We’ll advise you to get monitored at Dean Street Express or on line every 3-6 months.

What is Additional Private Care?

Additional Private Care where you buy extra healthcare on top of standard NHS care. In this case your sexual health screening and monitoring tests are provided free by the NHS. You’ll just pay for the prescribing and supply of the PrEP drugs.

You’ll need to sign some paperwork confirming you understand the following information.

We’ve also summarised it in the video.

  • If you buy ‘Additional Private Care’, your entitlement to NHS care is not affected.
  • The NHS part of your care remains the same as that of other NHS patients.
  • The private and NHS parts of your care will be kept as separate as possible.
  • You will not be charged for your 3-6 monthly PrEP monitoring.
  • The private part of your care will have the same quality assurance and audit checks as our NHS services.
  • If PrEP becomes available on the NHS in the future, you won’t be entitled to a refund.
  • HIV PrEP is available elsewhere. Ask one of our team for the latest information.
  • We will not be able to supply PrEP if you are no longer able to afford it.
  • We will not be able to prescribe generic PrEP if it is withdrawn from the UK market.
  • You’ll read the PrEP booklet provided by iBase.

Other ways to get HIV PrEP

PrEP Shop is just one way that you may be able to get HIV PrEP. There are several other options. People at very high risk of HIV may be eligible to get free NHS funded PrEP by joining the PrEP Impact study. It is also legal to purchase PrEP online from abroad and import up to 3 months supply into the UK for personal use. Terrence Higgins Trust list online suppliers that they recommend on the ‘I want PrEP now’ website.


Before you start using PrEP

  • PrEP contains 2 anti-HIV drugs called tenofovir and emtricitabine.
  • Before starting on PrEP you need a HIV, Hep B and kidney test.
  • People on medicines should check that there are no drug interactions with PrEP. You can check it HERE.
  • PrEP doesn’t protect against other STIs. That’s why people starting on PrEP can walk into Dean Street Express for a check-up without an appointment.

How to take daily PrEP

  • You have to take one tablet around the same time each day.
  • It takes 7 days before protection starts. After that you are still protected if you miss the occasional dose.
  • If your main risk is through condomless anal sex, you need to take at least 4 doses per week.
  • If your main risk is vaginal/front hole sex you need to take at least 6 doses per week.
  • If you decide to stop PrEP, you must take at least 2 doses after the last risk before you stop.


How to take event-based PrEP

  • In order to take PrEP ‘on demand’ you need to be able to predict sex in advance.
  • Taking PrEP on demand is only suitable for anal sex and it is important not to miss any doses.
  • You cannot use ‘on demand’ PrEP if you have active Hepatitis B infection.
  • On demand PrEP is as effective as daily PrEP when taken correctly.
  • Take 2 tablets 2-24hrs before sex and one tablet every 24hrs after the first dose.
  • You should continue taking PrEP until you have taken at least 2 doses after the last risk.