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PRIME THIS MONTH

The DoxyPEP effect?

Exciting news from the UK Health Security Agency (HSA). Their latest figures suggest syphilis has been falling in gay men since the end of 2024. 

At first glance that date seems too early for DoxyPEP to be the cause. DoxyPEP only became available on the NHS the following summer. However, Dean Street and other community organisations had heavily promoted the prevention pills since spring 24. Over 1 in 5 gay men told us that they’d already used DoxyPEP when picking up their first NHS prescription.

Gonorrhoea rates have remained similar, so it’s unlikely that the syphilis fall is because of a change in gay men’s sex lives. These are only preliminary figures so it’ll be interesting to see if the trend continues and if gonorrhoea rates begin to fall after the introduction of the vaccine.

On a less positive note the UKHSA reported more cases of antibiotic resistant gonorrhoea. That’s why prevention is important. We recommend all gay men complete 2 doses of the gonorrhoea vaccine (Bexsero).

More information here

Quarterly report on diagnoses of syphilis, gonorrhoea and ceftriaxone-resistant gonorrhoea in England: provisional data, March 2026 – GOV.UK

DoxyPEP & Bexsero – 56 Dean Street – Sexual Health Clinic London

Last month’s article

Last month, we discussed the new STI affecting gay men, Trichophyton.
PRIME – Last Month

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